Six children - who locals believe were possessed by spirits - started fitting and fainting at school without warning.
One of the young girls, while dressed in their school uniform, shouted out: "I will kill them" while in an apparent trance.
Video footage shows the youngsters being carried through the school grounds, some seemingly unconscious, while others fighting back at being restrained.
Their desperate parents have begged the church for help for their children, with one mother saying her daughter told her something was inside her.
The bizarre incident took place in a school in the small town of Palomino, Colombia.
Reports suggest that the students fainted without warning and the parents of the children do not know the cause.