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Roseanne Smith, 54, from Plano in Texas, watched in horror when at the age of 18 her ankle and foot began to swell without any explanation. Doctors were stumped by her unusual symptoms and as the years went on the swelling progressed up to her right leg and knees where it was rapidly growing in size. She was shunned for her unusually large limb, with strangers staring and cruelly gossiping about her.